4-AMINOPYRIDINE-3-CARBOXALDEHYDE, 4-BOC PROTECTED - Names and Identifiers
Name | TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE
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Synonyms | 4-(BOC-AMINO)-3-FORMYLPYRIDINE N-Boc-4-amino-3-formylpyridine N-BOC-4-AMINO-PYRIDINE-3-CARBOXALDEHYDE TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE N-BOC-4-AMINO-3-PYRIDINE CARBOXYALDEHYDE 4-AMINOPYRIDINE-3-CARBOXALDEHYDE, 4-BOC PROTECTED 4-Aminopyridine-3-carboxaldehyde, 4-BOC protected (3-FORMYL-PYRIDIN-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER Carbamic acid, N-(3-formyl-4-pyridinyl)-, 1,1-dimethylethyl ester
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CAS | 116026-93-8
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InChI | InChI=1/C11H14N2O3/c1-11(2,3)16-10(15)13-9-4-5-12-6-8(9)7-14/h4-7H,1-3H3,(H,12,13,15) |
4-AMINOPYRIDINE-3-CARBOXALDEHYDE, 4-BOC PROTECTED - Physico-chemical Properties
Molecular Formula | C11H14N2O3
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Molar Mass | 222.24 |
Density | 1.212g/cm3 |
Boling Point | 310°C at 760 mmHg |
Flash Point | 141.3°C |
Vapor Presure | 0.000618mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.579 |
4-AMINOPYRIDINE-3-CARBOXALDEHYDE, 4-BOC PROTECTED - Introduction
4-tert-butoxycarbonylamino-3-pyridinecarboxaldehyde, chemical formula C11H15N3O2, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
4-tert-Butoxycarbonylamino-3-pyridinecarboxaldehyde is a white crystalline solid with a melting point of 82-84°C. It is soluble in organic solvents such as ethanol, ether and chloroform.
Use:
4-tert-butoxycarbonylamino-3-pyridinecarboxaldehyde is a commonly used organic synthesis reagent, mainly used for the synthesis of other compounds. It can be used for the synthesis of spirocyclic ketones, imidazoles and fluorescent dyes. In addition, 4-tert-butoxycarbonylamino-3-pyridinecarboxaldehyde can also be used in the fields of pharmaceutical synthesis and dye industry.
Method:
There are many methods for preparing 4-tert-butoxycarbonylamino -3-pyridine carboxaldehyde. A common preparation method is to react 3-pyridinecarboxaldehyde with tert-butoxycarbonylhydrazine in an appropriate solvent, and to generate 4-tert-butoxycarbonylamino-3-pyridinecarboxaldehyde under the catalysis of sodium hydroxide or other bases.
Safety Information:
When using 4-tert-butoxycarbonylamino-3-pyridinecarboxaldehyde, the following safety information should be paid attention:
-It may be irritating to the skin, eyes and respiratory tract, so care should be taken to avoid direct contact during use.
-use to maintain good ventilation conditions, avoid inhalation of its vapor.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-If inhaled or exposed to the compound, rinse immediately with water and seek medical help.
-Avoid contact with oxidants and strong acids during storage and transportation.
-When using and disposing, please follow local regulations and operating procedures.
Last Update:2024-04-09 20:49:11